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HIIT

Interval training lowers insulin resistance and, when fasting glucose is raised, glucose. HDL rises a little more than with steady endurance work. Triglycerides and LDL get no row of their own.

Big LeverEffort: high

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Order of magnitude

Two to three HIIT sessions per week for at least two weeks. The dose comes from the HIIT studies, not from the endurance entry.

Jelleyman 2015: insulin resistance versus control SMD −0.49; fasting glucose −0.92 mmol/L only in the diabetes-risk subgroup. Batacan 2017: short-term HIIT lowered glucose in overweight, with no insulin or lipid-profile effect. Wood 2019: HIIT is not superior to MICT for TC, TG or LDL; it raises HDL 0.07 mmol/L more. Ferritin and uric acid stay without a row.

Effects in detail

Each row is a directed edge from our database, with range, latency, evidence grade and the condition under which it applies at all.

MarkerEffectLatencyMode of actionOutcomeEvidenceConditionSources
HOMA-IRhelps. Lowers 10–30 %

Derived from Jelleyman 2015 SMD −0.49 versus control, roughly 0.5 HOMA units if SD ≈ 1 at a baseline of 3.0. Batacan 2017 found no insulin effect. No separate insulin row.

2–12 weekschronicno
Evidence grade B
applies regardless of the starting value
Fasting glucosehelps. Lowers 10–18 %

Jelleyman 2015 −0.92 mmol/L only in diabetes risk or type 2 diabetes, at about 110 mg/dL. No overall effect in mixed samples. The row therefore only applies from 100 mg/dL.

2–12 weekschronicunclear
Evidence grade B
Glucose at or above 100 mg/dL

What this measure costs

Counteracting effects of the same measure.

No counteracting effect is on file for this measure. That does not mean there is none, only that we found no defensible edge.

Moves without implying progress

Informational or no established effect: the marker moves or was checked, and that is not progress.

MarkerEffectLatencyMode of actionOutcomeEvidenceConditionSources
HDL cholesterolmoves, and does not count. Raises 5–12 %

Wood 2019: +0.07 mmol/L HDL versus steady endurance training, counted on top of the aerobic HDL rise of about 2.1 mg/dL. Raising HDL is not a treatment goal.

4–12 weekschronicno
Evidence grade B
applies regardless of the starting value

Sources

Full details of every study the rows above rely on.

  1. Effects of exercise training on blood lipids: a systematic review and meta-analysis of randomised controlled trials

    Smart et al. · Sports Medicine · 2025 · Meta-analysis

    DOI 10.1007/s40279-024-02115-zPubMed 39331324

  2. The effects of high-intensity interval training on glucose regulation and insulin resistance: a meta-analysis

    Jelleyman et al. · Obesity Reviews · 2015 · Meta-analysis

    DOI 10.1111/obr.12317PubMed 26481101

  3. HIIT is not superior to MICT in altering blood lipids: a systematic review and meta-analysis

    Wood et al. · BMJ Open Sport & Exercise Medicine · 2019 · Meta-analysis

    DOI 10.1136/bmjsem-2019-000647PubMed 31921439

  4. Effects of high-intensity interval training on cardiometabolic health: a systematic review and meta-analysis of intervention studies

    Batacan et al. · British Journal of Sports Medicine · 2017 · Meta-analysis

    DOI 10.1136/bjsports-2015-095841PubMed 27797726